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Results and Publications


PhD theses

  • Hanne Bak Jensen (2012). Milk proteomics – linking genetic variants and isoform variation of milk proteins to technological properties of bovine milk. PhD Thesis, Aarhus University.
  • Ulrik Kræmer Sundekilde (2012). Milk metabolite variability and heritability and their association with technological properties of bovine milk elucidated by NMR-based metabonomics. PhD Thesis, Aarhus University.
  • Kristian Krag (2012). Quantitative milk genomics: Estimation of variance components and prediction of fatty acids in bovine milk. PhD Thesis, Aarhus University.
  • Vivi Raundahl Gregersen (2012). Quantitative trait loci and the relevance of phased haplotypes. PhD Thesis, Aarhus University.

 

Peer-reviewed articles

  • Krag  K, Poulsen NA, Larsen MK, Larsen LB, Janss LL, Buitenhuis  B Genetic parameters for milk fatty acids in Danish Holstein cattle based on SNP markers using a Bayesian approach BMC Genetics.2013, 14:79. DOI: 10.1186/1471-2156-14-79. URL: http://www.biomedcentral.com/1471-2156/14/79
  • Gustavsson, Frida; Buitenhuis, Albert (Bart); Johansson, Monika; Bertelsen, Henriette; Glantz, Maria; Poulsen, Nina; Lindmark-Månsson, Helena; Stålhammar, Hans; Bach Larsen, Lotte; Bendixen, Christian; Paulsson, Marie; Andrén, Anders (2013). Effects of breed and casein genetic variants on protein profile in milk from Swedish Red, Danish Holstein and Danish Jersey. J. Dairy Sci., in review.
  • Gregersen, V., Gustafsson, F., Glantz, M., Stålhammar, H., Andrén, A., Lindmark-Månsson, H., Poulsen, N.A., Larsen, L.B., Paulsson, M. & Bendixen, C. (2013). Genome wide association scans for bovine chromosomal regions affecting rheological parameters in rennet-induced skim milk gels. J. Dairy Sci., in review.
  • K. Krag, N. A. Poulsen, M. K. Larsen, L. B. Larsen, A. J. Buitenhuis (2013). Genetic parameters for fatty acids in Danish Holstein cattle based on SNP markers using a Bayesian approach. BMC Genetics, in review.
  • N. A. Poulsen, H. P. Bertelsen, H. B. Jensen, F. Gustavsson, M. Glantz, H. Lindmark Månsson, A. Andrén, M. Paulsson, C. Bendixen, A. J. Buitenhuis, L. B. Larsen (2013). The occurrence of non-coagulating milk and the association of bovine milk coagulation properties with genetic variants of the caseins in 3 Scandinavian dairy breeds. J. Dairy Sci., 96 (8), 4830-4842.
  • Sundekilde, UK, Larsen, LB & Bertram, HC (2013). NMR-based Milk Metabolomics. Metabolites  3(2), 204-222, doi:10.3390/metabo3020204.
  • A. J. Buitenhuis, U. K. Sundekilde, N. A. Poulsen, H. C. Bertram, L. B. Larsen, P. Sørensen (2013). Estimation of genetic parameters and detection of quantitative trait loci for metabolites in Danish Holstein Milk. J. Dairy Sci., 96(5), 3285-3295.
  • Sundekilde, U., Poulsen, NA, Bertram, HC & Larsen, LB (2013b). NMR metabonomics reveals strong association between milk metabolites and somatic cell count in bovine milk. J. Dairy Sci., 96(1), 290-299.
  • N. A. Poulsen, F. Gustavsson, M. Glantz, M. Paulsson, L.B. Larsen & M.K. Larsen (2012). The influence of Feed and Herd on Fatty Acid Composition in Three Dairy Breeds (Danish Holstein, Danish Jersey and Swedish Red). J. Dairy Sci., 95 (11), 6362-6371.
  • H.B. Jensen, N.A. Poulsen, K.K. Andersen, M. Hammershøj, H.D. Poulsen, L.B. Larsen (2012a). Distinct composition of bovine milk from Jersey and Holstein-Friesian cows with non, poor or good coagulation properties as reflected in protein genetic variants and isoforms determined by LC-ESI/MS. JDS, 95 (12), 6905-6917.
  • H. B. Jensen, J. W. Holland, N. A. Poulsen, and L. B. Larsen (2012b). Milk Protein Genetic Variants and Isoforms identified in Bovine Milk representing Extremes in Coagulation Properties. JDS 95, 2891-2903.
  • Ulrik K. Sundekilde, Daniela Barile, Mickael Meyrand, Nina A Poulsen, Lotte B Larsen, Carlito Lebrilla, Bruce German, Hanne C. Bertram (2012). Natural variability in bovine milk oligosaccharides from Danish Jersey and Holstein-Friesian breeds. JAFC 60, 6188-6196.
  • Jensen, HB, Poulsen, NA, Møller, HS, Stensballe, A, Larsen, LB (2012). Comparative proteomic analysis of casein and whey as prepared by chymosin-induced separation, isoelectric precipitation or ultracentrifugation. J. Dairy Res, 79 (04), 451-458.
  • Sundekilde, U., Frederiksen, P.D., Clausen, M., Larsen, L.B. & Bertram, H. (2011). NMR-based metabolomics reveals relationship between the metabolite profile and technological properties of bovine milk from two commercial breeds. J. Agric. Food Chem, 59(13), 7360-7367.
  • Frederiksen, P.D, Andersen, K.K., Hammershøj, M., Poulsen, H.D., Sørensen, J., Bakman, M., Qvist, K.B. & Larsen, L.B. (2011). Composition and effect of blending of noncoagulating, poorly coagulating and well-coagulating bovine milk from individual Danish Holstein cows. J. Dairy Sci., 94, 4787-4799.

 

Other science dissemination activities such as posters, abstracts and participation in congress etc.

  • Ulrik K. Sundekilde, Larsen L.B., Buitenhuis A.J., Larsen M.K., Andersen K.K., Bertram, H.C. (2014). NMR spectroscopic studies of “nature’s perfect food”. XII International Conference on the Applications of Magnetic Resonance in Food Science: Defining Food by Magnetic Resonance. Cesena, Italy May 20.-23. 2014.
  • BH Nielsen, P Andersen, LB Larsen, JF Young (2013). Purification and antioxidant capacity of β-casein genetic variants and their hydrolysates. Poster and sbstract, Infogest COST meeting, Madrid, April 2013.
  • M. Glantz, H. P. Bertelsen, F. Gustavsson, V. R. Gregersen, A. Andrén, H. Lindmark-Månsson, H. Stålhammar, N.A. Poulsen, L. B. Larsen, C. Bendixen, M. Paulsson. Effects of major genetic protein variants on acid-induced gelation properties in bovine milk. IDF World Dairy Summit, Yokohama, Japan, 28. Oct.- 1. Nov. 2013.
  • F. Gustavsson, H. P. Bertelsen, M. Glantz, H. Lindmark-Månsson, H. Stålhammar, N. A. Poulsen, L. B. Larsen, C. Bendixen, A. Andrén, M. Paulsson. Effect of casein genetic variants and composition on casein micelle size in Swedish Red. IDF World Dairy Summit, Yokohama, Japan, 28. Oct.- 1. Nov. 2013.
  • F. Gustavsson, H. P. Bertelsen, M. Glantz, H. Lindmark-Månsson, H. Stålhammar, N. A. Poulsen, L. B. Larsen, M. Paulsson & A. Andrén. Effect of casein genetic variants on rennet-induced gelation in Swedish Red. IDF World Dairy Summit, Yokohama, Japan, 28. Oct.- 1. Nov. 2013.
  • Nina Aagaard Poulsen, Albert Johannes Buitenhuis, Lotte Bach Larsen. The association of milk composition traits with milk coagulation properties in milk from healthy mid-lactating cows. 10.th International Symposium for Milk Genomics and Human Health, Oct. 1.-3., 2013, UC Davis, California.
  • Nina Aagaard Poulsen, Iga Rybicka, Albert Johannes Buitenhuis, Lotte Bach Larsen & Mette Krogh Larsen. Natural variation of riboflavin content in bovine milk. 10.th International Symposium for Milk Genomics and Human Health, Oct. 1.-3., 2013, UC Davis, California.
  • F. Gustavsson, V. R. Gregersen, A. J. Buitenhuis, H. P. Bertelsen,  M. Glantz, H. Stålhammar, H. LindmarkMånsson, N. A. Poulsen, L. B. Larsen, C. Bendixen, F. Fikse, A. Andrén & M. Paulsson. Investigation of rennet coagulation properties in milk from Swedish Red cows using both traditional and modern milk genomics approaches. 10th International Symposium for Milk Genomics and Human Health, Oct. 1.-3., 2013, UC Davis, California.
  • M. Glantz, V.R. Gregersen, F. Gustafsson, H. Stålhammar, A. Andrén, H. Lindmark-Månsson, N.A. Poulsen, L.B. Larsen, M. Paulsson & C. Bendixen (2012). Quantitative trait loci identified for acid-induced gelation properties in bovine milk. IDF World Dairy Summit, Cape Town, South Africa, November 4.-8. 2012.
  • Krag K, Poulsen NS, Larsen MK, Larsen LB, Buitenhuis AJ (2012). Genetic parameters for fatty acids in Danish Holstein cattle based on SNP markers using a Bayesian approach. Abstract and oral contribution p.2, 9.th International Symposium on Milk Genomics and Human Health, Wageningen, Oct. 8-10., 2012.
  • Larsen LB, Poulsen NA, Jensen HB, Gustavsson F, Glantz M, Gregersen VR, Bertelsen HP, Larsen MK, Sundekilde UK, Krag K, Pedersen KS, Bakman M, Nielsen JH, Lindmark-Månsson H, Stålhammar H, Bertram HC, Sørensen P, Buitenhuis B, Bendixen C, Andrén A & Paulsson  M. (2012). The Swedish-Danish Milk Genomics Initiative: Variation in milk phenotypes, effect on milk properties and underlying genetic influence in three Scandinavian breeds. Abstract p.17, 9.th International Symposium on Milk Genomics and Human Health, Wageningen, Oct. 8-10., 2012.
  • Poulsen NA, Bertelsen HP, Gustavsson F, Jensen HB, Glantz M, Andrén A, Lindmark-Månsson H, Bendixen C, Paulsson M, Buitenhuis B & Larsen LB (2012). The association of non-, poor and good coagulating milk with genetic milk protein variants in three Scandinavian dairy breeds. Abstract and poster, p. 27, 9.th International Symposium on Milk Genomics and Human Health, Wageningen, Oct. 8-10., 2012.
  • Nielsen BM, Najbjerg H, Jajcevic K, Pedersen P, Stagsted, J, Larsen LB & Young J (2912). Antioxidant potential of genetic variants of bovine kappa-casein in cell-based assays. Abstract and poster, p. 26, 9.th International Symposium on Milk Genomics and Human Health, Wageningen, Oct. 8-10., 2012.
  • Jensen HB, Poulsen NS & Larsen LB (2012). Genetic and isoform variability in relation to milk coagulation properties. Abstract, poster and oral contribution, p. 5, 9.th International Symposium on Milk Genomics and Human Health, Wageningen, Oct. 8-10., 2012.
  • Gustavsson F, Gregersen VR, Glantz M, Andrén A, Stålhammar H, Lindmark-Månsson H, Poulsen NA, Larsen LB, Paulsson M & Bendixen C (2012). Whole genome association scans for bovine chromosomal regions affecting rheology in rennet-induced gels. Abstract and poster, p. 15, 9.th International Symposium on Milk Genomics and Human Health, Wageningen, Oct. 8-10., 2012.
  • Gustavsson F, Johansson M, Bertelsen HP, Glantz M, Poulsen NA, Lindmark-Månsson H, Stålhammar H, Larsen LB, Bendixen C, Paulsson M & Andrén A (2012). Effect of genetic variants on milk composition and protein profile in three Scandinavian breeds. Abstract and poster, p. 14, 9.th International Symposium on Milk Genomics and Human Health, Wageningen, Oct. 8-10., 2012.
  • Andersen P, Jensen HB, Nielsen BM, Poulsen NS, Young J & Larsen LB (2012). Isolation of genetic variants of β-casein from bovine milk for structural and functional studies. Abstract and poster, p. 7, 9.th International Symposium on Milk Genomics and Human Health, Wageningen, Oct. 8-10., 2012.
  • Sundekilde UK, Poulsen NA, Buitenhuis AJ, Gustavsson F, Paulsson M, Larsen LB & Bertram HC (2012). Milk metabolite composition and its relation to nutritional and technological quality – a NMR metabolomics approach. Abstract, poster and oral contribution, p. 5, 9.th International Symposium on Milk Genomics and Human Health, Wageningen, Oct. 8-10., 2012.
  • Frida Gustavsson, Vivi Raundahl Gregersen, Maria Glantz, Anders Andrén, Hans Stålhammar, Helena Lindmark Månsson, Nina Aagaard Poulsen, Lotte Bach Larsen, Marie Paulsson, Christian Bendixen (2012). Whole genome association scans for bovine chromosomal regions affecting rheology in rennet-induced milk gels. Abstract submitted to 9.th International Symposium of Milk Genomics and Human Health. Wageningen Oct. 8.-10 2012.
  • Paulsson M. Mejeriteknologi, process och näring. Oral contribution. Workshop on Milk Quality, Svensk Mjölk, Stockholm, Sweden, Nov. 21-22, 2012.
  • Gustavsson F, Gregersen VR, Glantz M, Stålhammar H, Andrén A, Månsson HL, Poulsen NA, Larsen LB, Paulsson M, Bendixen C. Genome wide association studies for bovine chromosomal regions affecting rheological parameters in rennet-induced skim milk gels. Abstract and poster. IDF World Dairy Summit, Cape Town, South Africa Nov. 4-8, 2012.
  • Gustavsson F, Glantz M, Månsson HL, Stålhammar H, Andrén A, Poulsen NA, Buitenhuis B, Bendixen C, Larsen LB, Paulsson M. The Swedish-Danish Milk Genomics Initiative. Abstract and poster. IDF World Dairy Summit, Cape Town, South Africa Nov. 4-8, 2012.
  • Gustavsson F, Johansson M, Bertelsen HP, Glantz M, Poulsen NA, Lindmark-Månsson H, Stålhammar H, Larsen LB, Bendixen C, Paulsson M & Andrén A. Effect of genetic variants on milk composition and protein profile in three Scandinavian breeds. Abstract and poster. IDF World Dairy Summit, Cape Town, South Africa Nov. 4-8, 2012.
  • Gustavsson F, Glantz M, Stålhammar H, Andrén A, Lindmark Månsson H & Paulsson M. Skräddarsydd mjölk för olika mejeri-produkter (Tailored milk for different dairy products). Abstract and oral contribution. Djurhälso- & Utfodringskonferensen, Uppsala, Sweden, Aug. 21-22, 2012.
  • Gustavsson F & Paulsson M. The Danish-Swedish milk genomics initiative. Oral contribution. Workshop, Mjölkföretagardagarna, Helsingborg, Sweden, Feb. 16, 2012.
  • Larsen, L.B. The Danish-Swedish milk genomics initiative. Food for Health workshop, June 21-22, 2010, Faculty of Life Sciences, Frederiksberg (Lecture).
  • Poulsen, NA, Jensen, HB & Larsen, LB 2010, Coagulation properties in Danish Jersey and Holstein cows. Food for Health workshop, June 21-22, 2010, Faculty of Life Sciences, Frederiksberg (poster).
  • Jensen HB, Poulsen N, Holland J & Larsen LB (2010). Linking post-translational modifications of caseins to milk coagulation properties from Danish Holstein-Friesian cows. 7.th International Symposium on Milk Genomics and Human Health, UC Davis, Oct. 20.-22., 2010. (Abstract and poster).
  • Poulsen NA, Larsen MK & Larsen LB (2010). The influence of feed and genetic background on α-tocopherol and fatty acid content in milk from Danish Holsteins. 7.th International Symposium on Milk Genomics and Human Health, UC Davis, Oct. 20.-22., 2010 (Abstract and poster).
  • Sundekilde, U, Barile, D, Lebrilla, CB, German, JB, Larsen, LB & Bertram, HC 2010, Does natural genetic variability in Jersey and Holstein breeds affect bovine milk oligosaccharide abundance and composition?, Paper fremlagt ved 7th International Symposium on Milk Genomics and Human Health, UC Davis, USA. 20. - 22. October (abstract and poster).
  • Krag, K., L. L. Janss, M. M. Shariati, and A. J. Buitenhuis. 2010. Heritability Estimation Based On Small Sample Size Using SNP Markers. In: Proceedings of the 9th World Congress on Genetics Applied to Livestock Production, Leipzig, Germany. 1-6 August. CD-ROM communication no. 0654_PP3-80. (Peer reviewed conference article and poster).
  • Krag, K., L.L. Janss, M.M. Shariati, and A. J. Buitenhuis. 2010. Heritability Estimation Based On Small Sample Size Using SNP Markers. In: Book of abstracts of the 9th World Congress on Genetics Applied to Livestock Production, Leipzig, Germany. 1-6 August. PP3-80. p. 282. (Abstract).
  • Jensen HB, Poulsen NA, Holland J & Larsen LB, 2010, Linking post-translational modifications of bovine milk caseins to coagulation properties of individual cow's milk samples from Danish Holstein and Jersey cows (poster and abstract), præsenteret ved (i) 7th International Symposium on Milk Genomics & Human Health, 20-22 oktober 2010 i Davis, USA og (ii) Inter-Institute Poster Symposium, Institute for Molecular Bioscience, University of Queensland, 8. October 2010, Australia (poster).
  • Larsen, L.B. Hvilken rolle spiller “mælkens genetik” for sammensætning og kvalitet? Inviteret indlæg ved temamøde vedr. strategisk forskning i mælk og mælkekomponenter, Det strategiske Forskningsråd, Ingeniørforeningens Mødecenter, Copenhagen, 26. March 2009 (Lecture).
  • Larsen, L. B. Milk genomics – impact of genes for variation in milk composition and quality. Inviteret indlæg ved afsluttende mode i “The milk protein research consortium”, Laboratorium for Proteinkemi, Forskerparken, Molekylærbiologisk Institut, Aarhus Universitet, 29. January 2009 (Lecture).
  • Sundekilde, UK, Frederiksen, P. D., Larsen, LB & Bertram, HC (2009). Milk metabonomics: Prediction of technological and nutritional quality. FOOD Denmark Congress 24.-25. November, Copenhagen (abstract and poster).
  • Nina A. Poulsen, Lotte B. Larsen, Christian Bendixen, Mogens S. Lund, Hanne C. Bertram, Morten K. Larsen, Hanne B. Jensen, Ulrik Sundekilde, Bart Buitenhuis, Kristian Krag, Henriette Pasgaard, Hans Stålhammar, Helena Lindmark-Mansson, Anders Andrén, Marie Paulsson (2009).  The Danish/Swedish milk genomics initiative. Poster presented at the 6th International Symposium in Milk Genomics and Human Health, September 28-30, 2009, Paris, France (Lecture, abstract and poster).

  

Coverage

2013:

2012:

  • Mejeri, February: Jagten på den gode ko
  • Landbrug & Fødevarer, artikel: “Kvaliteten af den danske mælk er stigende. Samtidig forskes der i, hvordan den bliver endnu bedre. Mere klimavenlig, med sundere fedt, nye egenskaber og perfekt til ostefremstilling”. Feb. 2012. www.lf.dk/Aktuelt/Nyheder/2012/Februar/Supermælk.aspx
  • Newsletter, Livs- och läkemedelsportalen, Lund University, July 2012: Milk Genomics – kopplingen mellan kornas gener och mjölkens egenskaper.
  • Land Lantbruk, Aug. 2012 (n.o. 35), Artikel: Forskare söker ”ostgen”.
  • Avelsnytt, Dec. 2012 (n.o. 4), Artikel: Milk Genomics – kopplingen mellan kornas gener och mjölkens egenskaper.

2011:

2010:

2009:

  • Paulsson, M., Andrén, A., Stålhammar, H., Larsen, L.B., Lund, M.S., Bendixen, C., Bertram, H.C., Poulsen, N. A., Buitenhuis, B. & Lindmark-Månsson, H. (2009). Milk genomics- svensk-dansk forskningsprojekt i tiden. Forskning Special nr. 14, Svensk Mjölk, 9. september, 1-2 (artikel): 
    Milk genomics - svensk-danskst forskningsprojekt i tiden