Projects
Emmanouil Tsochatzis , Helen Gika & Adrian Covaci
Toxicity study of non-intentionally added substances (NIAS) present in polymer materials Description
01/09-2021 → 31/08-2024
Mogens Larsen , Martin Øvli Kristensen , Lars Wiking , Irene Fisker , Lotte Bach Larsen & Nina Aagaard Poulsen
Projektets mål er at øge anvendelsen af staldfodring med frisk græs som et led i at opnå en større andel hjemmeproduceret foder og derigennem at reducere miljø- og klimabelastningen fra dansk mælkeproduktion. Projektet vil undersøge staldfodring med frisk græs i både praksis besætninger og med de fistulerede køer på AU Viborg, som tilsammen vil skabe viden om foderoptag, mælkeproduktion og -kvalitet samt græssets proteinværdi når staldfodring med frisk græs er rygraden i foderrationen.
Projektet er finansieret af Mælkeafgiftsfonden.Description
01/01-2022 → 31/12-2024
Peter Ruhdal Jensen , Ivan Mijakovic , Nina Aagaard Poulsen , Jing Che , Julia Prangchat Stub Thomsen & Lotte Bach Larsen
In order to increase available food for the growing world population and at the
same time reducing climate impact of its production, more sustainable sources of
food proteins are urgently needed. In this context microbial production systems
are promising solutions. However, animal-derived proteins often carry protein
decorations and modifications that gives the proteins special properties and
functionalities. These modifications, scientifically denoted post-translational
modifications (PTMs), are overall linked to more advanced biological systems, and therefore microbes, and especially bacteria, are less capable of
producing. This constitutes a major bottleneck for using microorganisms as the
efficient expression vehicles they actually are for eg the very valuable animal
coded proteins. However, if we can decipher and rank the importance of PTMs
including essential sites and amount or degree of modification at each of these
sites are essential for protein functionality we can reduce the complexity of this
task.
The DECIPHER project initiative aims to remove these bottlenecks associated
with microbial production of proteins related to the milk system – the caseins –
and investigate and hopefully demonstrate the possibility of modifying the bovine
caseins in vitro after their microbial synthesis, and produce protein food
ingredients with comparable nutritional and functional properties as their native,
true animally produced original counterparts.
Description
01/04-2022 → 31/03-2025
Lotte Bach Larsen , Nina Aagaard Poulsen , Søren Drud-Heydary Nielsen , Stine Brandt Bering & Thomas Thymann
Most infant formulas (IF) are based on processed milk proteins, consisting of bovine whey proteins added to skimmed milk powder to obtain whey/casein (CN) ratio of 60/40 to approach the ratio in human milk (HM). The project aims to clarify the potential benefits of gently-processed intact or hydrolyzed micellar casein isolate (MCI) in IFs and how they compare to HM in terms of mild gastric clotting for improved gut comfort and motility and the release of bioactive peptides for improved gut health. It is currently unknown how the widely studied rennet-induced coagulation of bovine milk in relation to cheese-making properties translates into clotting properties in the infant stomach. This is studied in the CASGUT project; by combinations of piglet studies and lab based pilot experiments in the context of the established CASGUT AU/UCPH project consortium. Description
01/09-2022 → 31/08-2025