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Colon model system

TNO Intestinal Model-2 Manufactured by The TIM company.

  • Fecal samples are inoculated into the system to simulate the human colonic microbiota
  • The system can simulate the colonic environment such that, efflux from small intestinal digests of nutrients are present, intestinal movements are simulated (peristalsis), intestinal absorption of water/nutrients and anaerobicity of the colon is simulated. In addition pH and temperature within the system can be regulated and that the frequency and volume of output material can be controlled manually
  • The system can be used to model how different interventions/alterations of conditions (e.g. diet) impact the microbial communities and their activity in the human colon